Dental Implants - A History Of

The Mayan civilization has been shown to have used the earliest known examples of endosseous implants (implants embedded into bone), dating back over 1,350 years before Per-Ingvar Brånemark started utilizing titanium. While excavating Mayan burial sites in Honduras in 1931, archaeologists found a fragment of mandible of Mayan origin, dating from about 600 AD. This mandible, which is considered to be that of a woman in her twenties, had three tooth-shaped pieces of shell placed into the sockets of three missing lower incisor teeth. For forty years the archaeological world considered that these shells were placed after death in a manner also observed in the ancient Egyptians. However, in 1970 a Brazilian dental academic, Professor Amadeo Bobbio studied the mandibular specimen and took a series of radiographs. He noted compact bone formation around two of the implants which led him to determine that the implants were placed during life.

From the 1950s research was being conducted at Cambridge University in England to examine blood circulation in vivo. These workers devised a technique for constructing a chamber of titanium which was then embedded within the soft tissue of the ears of rabbits. In 1952 the Swedish orthopaedic surgeon, P I Brånemark, was interested in studying bone healing and regeneration, and adopted the Cambridge designed ‘rabbit ear chamber’ for use in the rabbit femur. Following many months of study he attempted to retrieve these expensive chambers from the rabbits and found that he wasunable to remove them. Per Brånemark observed that bone had grown into such close proximity with the titanium that it effectively adhered to the metal. Brånemark completed many further studies into this phenomenon, using both animal and human subjects, which all confirmed this unique property of titanium.

Meanwhile an Italian physician called Stefano Melchiade Tramonte, understood that titanium could be used for dental restorations and after designing a his own titanium screw to support dental prosthesis, started to utilize it on many patients in his clinic in 1959. The great results of his clinical studies on humans were published in 1966.

Although Brånemark had originally considered that the first work should target knee and hip surgery, he finally decided that the mouth was more accessible for continued clinical observations and the high rate of edentulism in the general population offered more subjects for widespread study. He termed the clinically observed adherence of bone with titanium as ‘osseointegration’. In 1965 Brånemark, who was by then the Professor of Anatomy at Gothenburg University in Sweden, placed his first titanium dental implant into a human volunteer, a Swede named Gösta Larsson.

Contemporaneous independent research in the usa by Stevens and Alexander led to a 1969 US patent filing for titanium dental implants.

Over the next fourteen years Brånemark published many studies on the application of titanium in dental implantology until in 1978 he entered into a professional partnership with the Swedish defense company, Bofors AB for the development and marketing of his dental implants. With Bofors (later to become Nobel Industries) as the parent company, Nobelpharma AB (later to be renamed Nobel Biocare) was founded in 1981 to focus on dental implantology. To the present day over 7 million Brånemark System implants have now been placed and hundreds of other companies produce dental implants. Nearly all dental implants currently available are shaped like small screws, with either tapered or parallel sides. They can be placed at the same time as a tooth is removed by engaging with the bone of the socket wall and sometimes also with the bone beyond the tip of the socket. Current evidence suggests that implants placed straight into an extraction socket have comparable success rates to those placed into healed bone.

The effectiveness and radiographic results of immediate restorations of dental implants put into fresh extraction sockets (the temporary crowns placed at the same time) have been shown to be comparable to those obtained with delayed loading (the crowns placed weeks or months later) in carefully selected cases.

Some current research in dental implantology is focusing on the use of ceramic materials such as zirconia (ZrO2) in the manufacture of dental implants. Zirconia is the dioxide of zirconium, a metal close to titanium in the periodic table and with similar biocompatability properties.

Although generally the same shape as titanium implants, zirconia, which has been used successfully for orthopaedic surgery for a number of years, has the advantage of being more cosmetically aesthetic owing to its bright tooth-like colour.However, long-term clinical data is necessary before one-piece ZrO2 implants can be recommended for daily practice.lotusclinic.co.uk
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